New Technology Poster Session
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Introduction
To evaluate the usefulness of Positron Emission Tomography with 18F-Fluordeoxyglucose (FDG-PET) to detect tumor recurrence on the basis of tumor marker increases, where negative results have been obtained with conventional methods (TC,RM,MN).
Materials and Methods
Whole-body FDG-PET was performed on 72 cancer patients: 23 with breast cancer, 18 colorectal cancer, 15 thyroid cancer, 6 lung cancer, 3 ovarian neoplasms and 7 other tumors. In all tumors, tumor recurrence was suspected on the basis of marker increases, and negative results had been obtained with conventional studies.
Results
FDG-PET detected lesions in 85% of the patients, which were confirmed in 33%. In 40% of all cases, therapeutic treatments were applied, and in 14% curative surgery was perfomed. Results are shown in the next table:
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TYPE OF N Study Total Confirmed Patients whose Patients who
TUMOR FDG-PET(+) PET-FDG PET-FDG Treatments were underwent surgery
Lesions Lesions Changed for curative purposes
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Breast 23 18 63 26 8 0
Colo-Rectal 18 17 34 11 9 5
Thyroid 15 12 34 14 5 4
Lung 6 6 21 0 0 0
Ovary 3 3 6 3 1 1
Other 7 5 8 1 6 0
TOTAL 72 61/72 166 55/166 29/72 10/72
85% 33% 40% 14%
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Discussion and Conclusion
Whole-body PET-FDG is a useful procedure in the diagnosis of recurring tumoral disease in patients with rising tumor marker levels, where negative results had been obtained with convencional methods.
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