Abstract

Introduction

Materials & Methods

Results

Discussion & Conclusion

References

Discussion
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Lysozyme was added to the serum as a source of C in CH50 whole C assays. Concentrations ranging from 50 to 1500 microgrammes per millilitre were added, corresponding to expected physiological and pathological levels of lysozyme in the colostrum, mature or inflammed breast-milk, as well as other normal and inflammed body fluids. Lysozyme was found to inhibit the classical pathway of serum complement activity in a dose-dependent fashion within the concentration ranges tested (Fig. 1).

Figure 1 Inhibitory effect of human purified lysozyme on serum complement activities

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