Arachidonic Acid Metabolites, Other Inflammatory Mediators and Intestinal Ion Transport

Grover
groverak@fhs.mcmaster.ca

On Thu Dec 10, P.K.Rangachari wrote
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>I tried to find some info about Isoprostanes and binding studies. there are precious few. Fukunaga et al (AJP 272:F477,1997) looked at binding of labelled 8-iso-PGF2alpha to rat mesangial cells and aortic smooth muscle cells.  On the former prep, they found a single class of low-affinity binding sites (Kd-0.47uM) whereas on the latter there were both high (32nM) and low 0.94uM sites.