Abstract

Introduction

Materials & Methods

Results

Discussion & Conclusion

References

Discussion
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Purpose : To assess the effects of Carteolol, a beta-blocker with ISA, on intraocular pressure, visual field and orbital blood circulation in eyes with chronic open angle glaucoma (COAG). Methods : We studied 30 patients (20 males and 10 females) aged 53 to 68 yrs. (mean 63.4 yrs) affected by COAG. Patients were assigned to a treatment group in a random, double masked fashion. Patients in group A were treated with Timolol 0.5% and in group B with Carteolol 2% in both eyes, twice daily. Patients examinations included pneumotonometry, authomatic perimetry and Color Doppler Imaging (CDI) by an Asynchronous-Hitachi analyzer with a 7.5 MHz linear probe in the ophthalmic artery and posterior ciliary arteries, before and after 18 months of therapy. Results : After 18 months of therapy, a reduction of resistence index was observed in patients treated with carteolol, in the posterior ciliary arteries (p < 0.001) with an improvement of MD (p < 0.002) and CPSD (p < 0.002) indexes of the authomatic perimetry. Conclusions : Carteolol 2% decreases the intraocular pressure to a lower extent than timolol 0.5%, but its effects on the visualt field and CDI indexes are better than timolol 0.5%.

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Poster Number PAcellini0571
Keywords: glaucoma, carteolol 2%, timolol 0.5%, CDI, blood circulation