Abstract

Introduction

Materials & Methods

Results

Discussion & Conclusion

References

Discussion
Board

Bartzokis, G., Aravagiri, M., Oldendorf, W.H., Mintz, J., Marder, S.R., 1993. Field dependent transverse relaxation rate increase may be a specific measure of tissue iron stores. Magnetic Resonance in Medicine 29, 459-464.

Bartzokis, G., Sultzer, D., Mintz, J., Holt, L.E., Marx, P., Phelan, C.K., Marder, S.R., 1994. In vivo evaluation of brain iron in Alzheimer's disease and normal subjects using MRI. Biol. Psychiatry 35, 480-487.

Bartzokis, G., 1997. Magnetic resonance imaging of brain iron. In: Connor, J.R. (Ed.), Metals and Oxidative Damage in Neurological Disorders. Plenum, New York, pp. 41-56.

Bons, N., Mestre, N., Petter, A., 1991. Senile plaques and neurofibrillary changes in the brain of an aged lemurian primate, Microcebus murinus. Neurobiol. Aging 13, 99-105.

Bons, N., Mestre, N., Ritchie, K., Petter, A., Podlisny, M., Selkoe, D., 1994. Identification of amyloid beta protein in the brain of the small, short-lived lemurian primate Microcebus murinus. Neurobiol. Aging 15, 215-220.

Bons, N., Jallageas, V., Mestre-Francés, N., Silhol, S., Petter, A., Delacourte, A., 1995. Microcebus murinus, a convenient laboratory animal model for the study of Alzheimer's disease. Alz. Res. 1, 83-87.

Bons, N., Silhol, S., Barbier, V., Mestre-Francés, N., Albe-Fessard, D., 1998. Microcebus murinus. Stereotaxic atlas and neurochemistry. Brain Res. Bull. x, xx-xx.

Chien, D., Edelman, R.R., 1991. Ultrafast Imaging Using Gradient Echoes. Magn. Reson. Quart. 7, 31-56.

Cooper, H. Atlas Stereotaxique de Microcebus murinus (unpublished manuscript available from H. Cooper, U371 INSERM, 18 avenue du Doyen Lepine, 69500 Bron, France).

Cullen, K.M., Halliday, G.M., Double, K.L., Brooks, W.S., Creasey, H., Broe, G.A., 1997. Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease. Neuroscience 78, 641-652.

Dedman, D.J., Treffry, A., Candy, J.M., Taylor, G.A.A., Morris, C.M., Bloxham, C.A., Perry, R.H., Edwardson, J.H., Harrison, P.M., 1992. Iron and aluminium in relation to brain ferritin in normal individuals and Alzheimer's disease and chronic renal-dyalisis patients. Biochem. J. 287, 509-514.

Dhenain, M., Michot, J.-L., Volk, A., Picq, J.-L., Boller, F., 1997. T2-weighted MRI studies of mouse lemurs: a primate model of brain aging. Neurobiol. Aging 18, 517-521.

Drayer, B.R., 1989. Basal ganglia: significance of signal hypointensity on T2-weighted images. Radiology 173, 311-312.

Fisel, C.R., Ackerman, J.L., Buxton, R.B., Garrido, L., Belliveau, J.W., Rosen, B.R., Brady, T.J., 1991. MR contrast due to microscopically heterogeneous magnetic susceptibility: numerical simulations and applications to cerebral physiology. Magn. Res. Med. 17, 336-347.

Gati, J.S., Menon, R.S., Ugurbil, K., Rutt, B.K., 1997. Experimental determination of the BOLD field strength dependence in vessels and tissue. Magn. Res. Med. 38, 296-302.

Good, P.F., Perl, D.P., Bierer, L.M., Schmeidler, J., 1992. Selective accumulation of aluminium and iron in the neurofibrillary tangles of Alzheimer's disease. Ann. Neurol. 31, 286-292.

Haase, A., Frahm, J., Matthaei, D., 1986. FLASH Imaging: Rapid NMR Imaging Using Low Flip-Angle Pulses. J. Magn. Reson. 67, 258-266.

Hallgren, B., Sourander, P., 1958. The effect of age on the non-haemin iron in the human brain. J. Neurochem. 3, 41-51.

Lee, D.H., 1991. Mechanisms of contrast enhancement in magnetic resonance imaging. Can. Assoc. Radiol. J. 42, 6-12.

Lee, J.-H., Garwood, M., Menon, R., Adriany, G., Andersen, P., Truwit, C.L., Ugurbil, K., 1995. High contrast and fast three-dimensional magnetic resonance imaging at high fields. Magn. Res. Med. 34, 308-312.

Lee, J.T., Miller, C.A., McDonald, C.T., Allman, J.M., 1996. Xanthogranuloma of the choroid plexus in the fat-tailed dwarf lemur (Cheirogaleus medius). Am. J. Primatol. 38, 349-355.

Mestre, N., Bons, N., 1993. Age-related cytological changes and neuronal loss in basal forebrain cholinergic neurons in Microcebus murinus (lemurian, primate). Neurodegeneration 2, 25-32.

Mestre-Francés, N., Silhol, S., Bons, N., 1996. Evolution of b-amyloid deposits in the cerebral cortex of Microcebus murinus lemurian primate. Alz. Res. 2, 19-28.

Narasimhan, P.T., Ghosh, P., Fraser, S.E., Jacobs, R.E., 1994. Magnetic resonance microscopy: challenges in biological imaging using a 500 MHz NMR microscope. Proc. Ind. Acad. Sci. 106, 1625-1641.

Narasimhan, P.T., Jacobs, R.E., 1996. Neuroanatomical micromagnetic resonance imaging. In: Toga, A.W.; Mazziotta, J.C. (Eds.), Brain Mapping: The Methods. Academic Press, New York, pp. 147-167.

Pearse, A.G.E., 1961. Histochemistry. Theoretical And Applied. J. & A. Churchill, London.

Schenck, J.F., 1995. Imaging of brain iron by magnetic resonance: T2 relaxation at different field strengths. J. Neurol. Sci. 134 (Suppl.), 10-18.

Vymazal, J., Brooks, R.A., Patronas, N., Hajek, M., Bulte, J.W.M., Di Chiro, G., 1995. Magnetic resonance imaging of brain iron in health and disease. J. Neurol. Sci. 134 (Suppl.), 19-26.

Back to the top.