Arachidonic Acid Metabolites,
Other Inflammatory Mediators and Intestinal Ion Transport
Question for Dr. Barrett (or anyone else who cares to answer) W.K. MacNaughton
wmacnaug@ucalgary.ca
Kim, nice review of a complicated topic. What is known of the role of mast cell-derived proteases in regulating transport? I know that the effect of rat mast cell protease II (RMCP-II) has been tested on epithelial permeability, but effects on ion transport are less clear. Is there, to your knowledge, a physiological role for serine proteases in ion transport, either physiological or pathophysiological?
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Fri Dec 11