Arachidonic Acid Metabolites,
Other Inflammatory Mediators and Intestinal Ion Transport
Response to MacNaughton P.K.Rangachari
chari@fhs.mcmaster.ca
You asked whether the non-PG metabolites affect expression of COXs. I do not know. But that is worth exploring. Several of the epoxides are commercially available and in the absence of selective antagonists, one can use stereochemical specificity as an index of effectiveness.
Tue Dec 15