Pharmacology & Toxicology Poster Session

Re^2: Poster 775:Thanx

Dr. Gros:
Thanx for the response.
akg

On Mon Dec 14, Robert Gros wrote
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>Dear Dr Grover,

>Thanks for the comment and yes I am enjoying the meeting. You are right, the northern blot data would suggest that GRK-2 mRNA is not the answer for the increase in GRK-2 protein expression. Altered protein stability in a strong possibility as a potential explanation for the increase in GRK-2 protein expression in both human and rat lymphocytes and rat vascular tissues.
>
> Thanks for your comments,

> Rob Gros
>
>
>
> On Sun Dec 6, Grover wrote
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>>"Dr. Gros: I am glad to see your nice presentation and hope you enjoy the meeting. You conclude that the increased GRK-2 protein content in hypertension is not due to an increase in GRK-2 messenger RNA. Do you think then the mechanism involves a difference in protein stability or translation?"
>>
>

Mon Dec 14