Abstract

Introduction

Materials & Methods

Results

Discussion & Conclusion

References

Discussion
Board

The present study has clearly demonstrated that electrochemotherapy is an effective treatment for decreasing tumor volume of the metastatic lesion of hamster oral fibrosarcoma. Thus, in vivo, the local potentiation of CPA by the electrochemotherapy results in substantial anticancer acting even with the administration of small amounts of drug which limits side-effects. The effects of other anticancer drugs as well as their minimal effective dose with electric pulses should be further studied. In addition, efforts are under way to examine various routes of administration of the anticancer drugs and ways to increase the effectiveness of the therapy. The results from this experimental animal studies will be instrumental in using this treatment for the clinic.

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