Reduction of lower motor neuron degeneration in wobbler mice by N-acetylcysteine

Jeffrey T. Henderson, Mohammed Javaheri, Susan Kopko and John C. Roder

Samuel Lunenfeld Research Institute, Mount Sinai Hospital,
Program in Molecular Biology and Cancer, 600 University Ave., Toronto, Ontario M5G-1X5

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Figure 3. NAC reduces the loss of ChAT-positive motor neurons within the cervical spinal cord of wobbler mice at 9 weeks of age.

Total numbers of choline acetyl transferase positive neurons are indicated for each group (n=4). Numbers represent counts from every 5th section in a serial series of 10 micron transverse sections through the entire c4-c7 region. Values represent the mean +S.E.M.,(*) signifies a significant difference (p<0.05) compared to wr/wr group.