Quinones and Other Reactive Oxygen Species in Neurobiologic, Apoptotic, and Neurotoxic Processes

Toxicity of dopamine/dopaminochrome on cultured cells

Your findings indicate that genetics have an important role in protecting neurons from oxidative damage. Those kinds of cells with an enzymatic composite that produce a high level of antioxidant defenses are least susceptible to oxidative injury. However, it is difficult to establish a familial line in Parkinson's disease. In other words, except for isolated studies, there does not appear to be a genetic basis for Parkinson's disease. Can you please put your findings in this context to address the possible link in your studies to susceptibility to Parkinson's disease?

Tue Dec 15