Quinones and Other Reactive
Oxygen Species in Neurobiologic, Apoptotic, and Neurotoxic Processes
No title! Jean Lud Cadet, M.D.
jcadet@intra.nida.nih.gov
Professor Smythies has offered an impressive review about what we know and do not know about catecholamines. It is interesting, however, that there are abnormalities in non-catecholaminergic systems even in those disorders that are thought to be mediated by monoaminotoxins. Is it possible that there exists in these disorders a primary genralized toxin whose toxicity is exacerbated in catecholaminergic neurons? If that is the case, is our emphasis on dopamine as a toxin exaggerated? I would like to hear what others think about this.
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Thu Dec 10