Cell Biology Poster Session

Re: Poster 296

On Sun Dec 6, grover wrote
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>Dr. Brooks: Fascinating results. Hope you are having fun at the meeting. I was really fascinated that PFK had a Q10 of 3.6. Two questions: is it known what is in the PFK molecular structure which results in such a high Q10? Is this the same PFK which is present in most mammalian cells or a different isozyme? Finally, I am glad that this frog does not have to live in the hot weather.
>
Thanks for the comments. We presume that the PFK either exists already in an altered state via phosphorylation to change its physical characteristics or that it must be a radically different isozyme of PFK. PFK is known to be terribly sensitive to polymerization/depolymerization and temperature may have a significant
role in this process. As to a PFK with a Q10 of 3.6 already existing - I don't know of another PFK that has a Q10 in this range but most of the invertebrate PFKs have not been tested for temperature effects by themselves.

SteveB.

Mon Dec 14